Product Description
Quinine hydrochloride
Quinine hydrochloride is a medication that is used to treat malaria. It is a salt of quinine, which is a natural alkaloid found in the bark of the cinchona tree. Quinine hydrochloride works by interfering with the growth and reproduction of the malaria parasites in the body. It does this by disrupting the parasite’s ability to make ATP, which is a molecule that provides energy for the parasite. Quinine hydrochloride is also thought to damage the parasite’s cell membrane, which can lead to the parasite’s death.
Quinine hydrochloride is an effective treatment for malaria, but it can also have side effects, such as nausea, vomiting, and diarrhea. In some cases, quinine hydrochloride can also cause more serious side effects, such as liver damage and hearing loss. For this reason, quinine hydrochloride should only be used under the supervision of a doctor.
Here are some additional information about quinine hydrochloride:
- Dosage: The dosage of quinine hydrochloride will vary depending on the patient’s age, weight, and medical condition.
- Side effects: The most common side effects of quinine hydrochloride are nausea, vomiting, and diarrhoea. In some cases, quinine hydrochloride can also cause more serious side effects, such as liver damage and hearing loss.
- Interactions: Quinine hydrochloride can interact with a number of other medications, including antibiotics, anticonvulsants, and heart medications.
- Overdose: Quinine hydrochloride overdose can be fatal. If you think you or someone you know has overdosed on quinine hydrochloride, call 911 or the Poison Control Center immediately.
Identification
Molecular Formula : C20H25CIN2O2, 2H2O
Cas No. : 6119-47-7
Regulatory Documents
USDMF :
EDMF :
Batch Size : 300 Kgs.
Specifications
Appearance : White or almost white or colourless, fine, silky needles, often in clusters.
Solubility
Soluble in water, freely soluble in ethanol (96 per cent).
Specific Optical Rotation : -245.0° to -258.0°C at 20°C
Loss On Drying : 6.0 % To 10.0 %
pH : 6.0 to 6.8
Sulfated ash : Not more than 0.10%
Barium : To Complies the test as per BP/EP
Sulfates : Not more than 500ppm
Assay
Quinine hydrochloride : 99.0 % to 101.0 % (dried substance)
Other cinchona alkaloids By HPLC
Dihydroquinine impurity C : ≤ 10.0%
Any related substance Eluted before quinine : ≤ 5.0 %
Any other related substance : ≤ 2.5 %