Product Description
Cinchonine is a cinchona alkaloid that has been used for centuries to treat malaria. It is less potent than quinine, but it can still be effective in treating malaria, especially in areas where malaria parasites are not resistant to cinchonine.
Cinchonine is generally safe when used as directed. However, it can cause some side effects, such as nausea, vomiting, diarrhoea, headache, and ringing in the ears. In rare cases, cinchonine can cause more serious side effects, such as liver damage, heart problems, and seizures.
If you are taking cinchonine, it is important to talk to your doctor about the risks and benefits of the medication. You should also follow your doctor’s instructions carefully to avoid side effects.
Here are some additional information about cinchonine:
- It is available in tablet and capsule form.
- The dosage of cinchonine will vary depending on your age, weight, and medical condition.
- You should take cinchonine with food to reduce stomach upset.
- You should not drink alcohol while taking cinchonine.
- If you miss a dose of cinchonine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose as scheduled. Do not take two doses of cinchonine at the same time.
- If you have any questions or concerns about taking cinchonine, talk to your doctor.
Identification
Molecular Formula : C19H22N2O
Cas No. : 118-10-5
Regulatory Documents
USDMF :
EDMF :
Batch Size : 50 Kgs.
Specifications
Appearance : White crystalline powder.
Solubility
Soluble in wateVery slightly soluble in water, sparingly soluble in ethanol (96%) and in methanol
Specific Optical Rotation : -225.0° to -230.0°C at 20°C
Loss On Drying : Not more than 1.0%
pH : 7.0 to 8.5
Residue on ignition : Not more than 0.50%
Assay
Cinchonine : 98.0 % to 101.0 % (dried substance)
Other cinchona alkaloids By HPLC
Dihydrocinchonine : ≤ 20.0%
Quinidine : ≤ 4.0 %
Quinine : ≤ 4.0 %