Product Description
Quinine Dihydrochloride
Quinine dihydrochloride is a medication that is used to treat and prevent malaria. It is a derivative of the cinchona tree, and it has been used for centuries to treat malaria. Quinine dihydrochloride works by interfering with the growth and reproduction of the malaria parasite. It does this by inhibiting the parasite’s ability to convert hemoglobin, a component of red blood cells, into a form that the parasite can use for energy. This disrupts the parasite’s lifecycle and reduces its ability to cause harm.
Quinine dihydrochloride is generally safe when used as directed. However, it can cause some side effects, such as nausea, vomiting, diarrhea, headache, and ringing in the ears. In rare cases, quinine dihydrochloride can cause more serious side effects, such as liver damage, heart problems, and seizures.
If you are taking quinine dihydrochloride, it is important to talk to your doctor about the risks and benefits of the medication. You should also follow your doctor’s instructions carefully to avoid side effects.
Here are some additional information about quinine dihydrochloride:
- It is available in tablet, capsule, and liquid form.
- The dosage of quinine dihydrochloride will vary depending on your age, weight, and medical condition.
- You should take quinine dihydrochloride with food to reduce stomach upset.
- You should not drink alcohol while taking quinine dihydrochloride.
- If you miss a dose of quinine dihydrochloride, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose as scheduled. Do not take two doses of quinine dihydrochloride at the same time.
- If you have any questions or concerns about taking quinine dihydrochloride, talk to your doctor.
Identification
Molecular Formula : C20H24N2O2, 2HCl
Cas No. : 60-93-5
Regulatory Documents
USDMF :
EDMF :
Batch Size : 300 Kgs.
Specifications
Appearance : A White or almost white powder.
Solubility
Very Soluble in water, Soluble in ethanol (96 per cent).
Specific Optical Rotation : -223.0° to -229.0°C at 20°C
Loss On Drying : Not more than 3.0%
pH : 2.0 to 3.0
Sulfated ash : Not more than 0.10%
Barium : To Complies the test as per BP
Sulfates : To Complies the test as per BP
Assay
Quinine Dihydrochloride : 99.0 % to 101.0 % (dried substance)
Other cinchona alkaloids By HPLC
Dihydroquinine impurity C : ≤ 10.0%
Any related substance Eluted before quinine : ≤ 5.0 %
Any other related substance : ≤ 2.5 %