Product Description

Quinine Bisulfate is an alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient

Identification

Molecular Formula   :     C20H24N2O2, H2SO4, 7H2O

Cas No.                       :     549-56-4

Regulatory Documents

USDMF                      :     

EDMF                         :     

Batch Size                 :     300 Kgs.

Quinine Bisulphate
Quinine Bisulphate

Specifications

Appearance   :     Colorless crystals or a white, Crystalline powder; efflorescent in dry air.

Solubility

Freely soluble in water, sparingly soluble in ethanol (96 %).

Specific Optical Rotation   :     -208.0° to -216.0°C at 20°C

Water Determination         :     19.0 % to 25.0 %

pH                                          :     2.8 to 3.4

Sulfated ash                         :     Not more than 0.10%

Titratable Cation                  :     75.3% to 79.6% (On anhydrous Basis)

Assay

Quinine Bisulfate   :     98.5 % to 101.5 % (anhydrous substance)

Other cinchona alkaloids By HPLC

Dihydroquinine ( impurity C)                                      :      ≤ 10.0%

Any related substance Eluted before quinine         :     ≤ 5.0 %

Any other related substance                                      :     ≤ 2.5 %