Product Description
Quinine Bisulfate is an alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient
Identification
Molecular Formula : C20H24N2O2, H2SO4, 7H2O
Cas No. : 549-56-4
Regulatory Documents
USDMF :
EDMF :
Batch Size : 300 Kgs.
Specifications
Appearance : Colorless crystals or a white, Crystalline powder; efflorescent in dry air.
Solubility
Freely soluble in water, sparingly soluble in ethanol (96 %).
Specific Optical Rotation : -208.0° to -216.0°C at 20°C
Water Determination : 19.0 % to 25.0 %
pH : 2.8 to 3.4
Sulfated ash : Not more than 0.10%
Titratable Cation : 75.3% to 79.6% (On anhydrous Basis)
Assay
Quinine Bisulfate : 98.5 % to 101.5 % (anhydrous substance)
Other cinchona alkaloids By HPLC
Dihydroquinine ( impurity C) : ≤ 10.0%
Any related substance Eluted before quinine : ≤ 5.0 %
Any other related substance : ≤ 2.5 %